Nucleo Research

Nucleo Research, a Y Combinator-backed startup founded by Angelica Iacovelli and team, automates CT scan analysis for oncology care, delivering results in seconds instead of hours. It performs automatic body composition and sarcopenia assessment, quantifying fat and muscle mass, along with precise, consistent tumor lesion sizing in CT scans. Lesions are classified per RECIST criteria (target vs. non-target), with analysis substantially faster than manual segmentation while achieving strong agreement with expert radiologists. Nucleo integrates with leading hospitals and industry partners, with custom enterprise pricing available via demo.